New anti-HIV antibody function discovered: Tethering of viral particles at the surface of cells

Researchers have discovered a new function of anti-HIV-1 antibodies by applying cutting-edge microscopy techniques to in vitro viral cultures. The scientists found that certain antibodies already known for effectively targeting HIV-1 envelope (Env) protein can prevent infected cells from releasing viral particles, thus halting viral spread. The findings demonstrate that these powerful antibodies exhibit different antiviral activities in addition to neutralization.