Phage therapy research brings scientists a step closer to harnessing viruses to fight antibiotic resistance

Phage therapy is the concept of using viruses (known as phage) to kill bacteria, instead of using antibiotics. Until now, experiments have largely focussed on exposing bacteria to phage in a flask. Now, researchers have developed a new way to mimic these microenvironments, in which a single bacterium would colonize a specific area. Using this method, the team found that in these microenvironments Escherichia coli, a bacterium that is often responsible for food poisoning, does not become genetically resistant to phage, and the majority of the bacterial population is killed by phage.