The drug aprotinin inhibits entry of SARS-CoV2 in host cells, study finds

In order for the SARS-CoV2 virus to enter host cells, its ‘spike’ protein has to be cleaved by the cell’s own enzymes — proteases. The protease inhibitor aprotinin can prevent cell infection, as scientists have now discovered. An aprotinin aerosol is already approved in Russia for the treatment of influenza and could readily be tested for the treatment of COVID-19.